主要研究方向:天然药物抗病毒机制研究;墨旱莲抗金黄色葡萄球菌有效成分的分离与鉴定。
硕博期间主要开展猪繁殖与呼吸综合征病毒的抗体依赖性增强作用、炎症反应信号通路和甘草酸抗病毒等方面的研究工作。先后参加国家自然科学基金重大项目、国家973计划项目、教育部重点课题、国家自然科学青年基金项目等多项科研课题。现主持河南工业大学高层次人才科研启动基金项目1项。
代表性论文:
[1]
Duan E, Wang D, Luo R, Luo J, Gao L, Chen H, Fang L*, Xiao S*. Porcine reproductive and respiratory syndrome virus infection triggers HMGB1 release to promote inflammatory cytokine production. Virology. 2014, 468-470C: 1-9.
[2]
Duan E, Wang D, Fang L, Ma J, Luo J, Chen H, Li K, Xiao S*. Suppression of porcine reproductive and respiratory syndrome virus proliferation by glycyrrhizin. Antiviral Res. 2015, 120:122-125.
[3]
段二珍,周永辉,张宜娜,张继希,张志远,卢晓艳,刘肖萍,夏平安*,崔保安. FcγR II B介导的PRRSV感染的抗体依赖性增强作用. 中国兽医学报,2012, 32(8) : 1105-1109.
[5]
Wang D, Fang L, Li K, Zhong H, Fan J, Ouyang C, Zhang H, Duan E, Luo R, Zhang Z, Liu X, Chen H, Xiao S*. Foot-and-mouth disease virus 3C protease cleaves NEMO to impair innate immune signaling. J Virol. 2012, 86 (17): 9311-9322.
[6]
Mu C, Lu X, Duan E, Chen J, Li W, Zhang F, Martin DP, Yang M, Xia P*,CuiB*.Molecularevolutionof porcine reproductive and respiratory syndrome virus isolates from central China. Res Vet Sci. 2013, 95 (3): 908-912.
[7]
Xia P, Liu X, Zhang Y, Duan E, Zhang Z, Chen J, Mu C, Cui B*. Porcine Fc gamma RIIb sub-isoforms are generated by alternative splicing. Vet Immunol Immunopathol. 2012, 145: 386-394.
[8]
Zhang Y, Zhou Y, Yang Q, Mu C, Duan E, Chen J, Yang M, Xia P*, Cui B*. Ligation of Fc gamma receptor IIB enhances levels of antiviral cytokine in response to PRRSV infection in vitro. Vet Microbiol. 2012, 160: 473-480.
[9]
Xia P, Liu Y, Liu X, Zhang Z, Duan E, Lu X, Zhao J, Cui B*. Molecular cloning and characterization of a porcine Fc gamma RIIb sub-isoform (FcγRIIb1).Vet Immunol Immunopathol. 2011, 141 (1-2): 144-150.
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