姓名： 董臣

性别：男

学历：博士

职称：副教授

招生方向： 1、萜类物质合成的分子机制解析及关键酶的理性设计；2、食品加工与安全

联系方式：chen.dong@haut.edu.cn

个人简介

主要对植物萜类代谢途径中的关键分支酶进行研究，分析萜类物质合成的调控机制；通过理性设计对萜类物质合成关键酶进行改造，实现植物酶的人工智能设计，调控整个萜类物质合成的代谢流。主持完成国家自然科学基金项目1项，河南省自然科学基金面上项目1项，河南省科技攻关项目1项，以及河南省教育厅项目1项。以第一作者或者通讯作者在Science Bulletin，IJMS, Genes, RSC Advances，Plant Growth Regulation，Plant Cell Tissue And Organ Culture等发表SCI论文10余篇，参与申报发明专利17项。

代表性论文：

1. Du F^#., Hu ZY^#., Qin LL^#., Zhang C., Wang ZW., Shi YC., Wang XR., Wang R., Gao YL*., Dong C^*. Suppression of carotenoid cleavage dioxygenase 1 (NtCCD1) increases carotenoid contents and attenuates reactive oxygen species (ROS) in Tobacco Leaves. Plant Growth Regul. 2023; https://doi.org/10.1007/s10725-023- 00961-x

2. Dong C., Zhang M., Song S., Wei F., Qin LL., Fan P., Shi Y., Wang X., Wang R^*. A Small Subunit of Geranylgeranyl Diphosphate Synthase Functions as an Active Regulator of Carotenoid Synthesis in Nicotiana tabacum. Int. J. Mol. Sci. 2023; 24:992.

3. Qin LL., Du F., Yang NN., Zhang C., Wang ZW., Zheng XW., Tang JW., Yang LB., Dong C^*. Transcriptome Analyses Revealed the Key Metabolic Genes and Transcription Factors Involved in Terpenoid Biosynthesis in Sacred Lotus. Molecules. 2022; 27:4599.

4. Dong C^#., Wang QD^#., Wang YB., Qin LL., Shi YC., Wang XR., Wang R^*. NtDREB-1BL1 Enhances Carotenoid Biosynthesis by Regulating Phytoene Synthase in Nicotiana tabacum. Genes. 2022; 13:1134.

5. Dong C^#., Qu G^#., Guo JG^#., Wei F., Gao SW., Sun ZT., Jin LF., Sun XW., Rochaix JD., Miao YC^*., Wang R^*. Rational Design of Geranylgeranyl Diphosphate Synthase Enhances Carotenoid Production and Improves Photosynthetic Efficiency in Nicotiana tabacum. Sci Bull. 2022; 67:315-327.

6. Dong C^#., Zhang M^#., Wei F^#., Guo YS., Qin LL., Wei P., Wang YB., Jin LF., Song WN., Sun T., Li F., Wang R^*. Inhibition of red chlorophyll catabolite reductase improved chlorophyll and carotenoid synthesis in tobacco, Plant Cell Tiss Org. 2022; 148(3): 687-698.